SNU CBE

Microbial Metabolic Engineering and Bioproduction

연구주제 · Molecular Biology

참여 교수

교수연구분야논문
한지숙생물 및 환경32
서상우생물 및 환경27
김준원생물 및 환경11
유동원고분자 및 유기 소재 · 생물 및 환경1
이종민공정시스템1
정상택생물 및 환경1

연결되는 NTIS 분류

생물화학 공정기술 21 화학공정 1

논문 (피인용 순)

연도논문학부 저자피인용
2018Efficient production of lycopene in Saccharomyces cerevisiae by enzyme engineering and increasing membrane flexibility and NAPDH production
Applied Microbiology and Biotechnology
한지숙131
2015Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyces cerevisiae
Applied Microbiology and Biotechnology
한지숙119
2015Efficient production of 2,3-butanediol in Saccharomyces cerevisiae by eliminating ethanol and glycerol production and redox rebalancing
Metabolic Engineering
한지숙113
2018Systems assessment of transcriptional regulation on central carbon metabolism by Cra and CRP
Nucleic Acids Research
서상우102
2017Improvement of d ‐Lactic Acid Production in Saccharomyces cerevisiae Under Acidic Conditions by Evolutionary and Rational Metabolic Engineering
Biotechnology Journal
한지숙97
2018Design and optimization of genetically encoded biosensors for high-throughput screening of chemicals
Current Opinion in Biotechnology
서상우89
2016Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase
Scientific Reports
한지숙88
2014Metabolic engineering of Saccharomyces cerevisiae for the production of isobutanol and 3-methyl-1-butanol
Applied Microbiology and Biotechnology
한지숙87
2019Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae
Nature Communications
서상우79
2014Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels
Scientific Reports
서상우78
2017Precise flux redistribution to glyoxylate cycle for 5-aminolevulinic acid production in Escherichia coli
Metabolic Engineering
서상우76
2018Synthetic auxotrophs for stable and tunable maintenance of plasmid copy number
Metabolic Engineering
서상우72
2014Reconstruction of a high‐quality metabolic model enables the identification of gene overexpression targets for enhanced antibiotic production in Streptomyces coelicolor A3(2)
Biotechnology Journal
김준원71
2019Efficient production of d-lactate from methane in a lactate-tolerant strain of Methylomonas sp. DH-1 generated by adaptive laboratory evolution 생물화학 공정기술 › 대사공학기술
Biotechnology for Biofuels
한지숙62
2019In silico identification of metabolic engineering strategies for improved lipid production in Yarrowia lipolytica by genome-scale metabolic modeling
Biotechnology for Biofuels
김준원61
2015Pathway optimization by re-design of untranslated regions for L-tyrosine production in Escherichia coli
Scientific Reports
서상우61
2022Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction 생물화학 공정기술 › 대사공학기술
Metabolic Engineering
한지숙61
2018Metabolic Engineering of Saccharomyces cerevisiae for Production of Shinorine, a Sunscreen Material, from Xylose
ACS Synthetic Biology
한지숙47
2020Independent component analysis of E. coli's transcriptome reveals the cellular processes that respond to heterologous gene expression
Metabolic Engineering
서상우44
2017Synthetic redesign of Escherichia coli for cadaverine production from galactose
Biotechnology for Biofuels
서상우41
2021Synthetic biosensor accelerates evolution by rewiring carbon metabolism toward a specific metabolite 생물화학 공정기술 › 대사공학기술
Cell Reports
서상우41
2023Programmable synthetic biology tools for developing microbial cell factories
Current Opinion in Biotechnology
서상우40
2019Synthetic biology for evolutionary engineering: from perturbation of genotype to acquisition of desired phenotype
Biotechnology for Biofuels
서상우40
2014Synthetic scaffold based on a cohesin–dockerin interaction for improved production of 2,3-butanediol in Saccharomyces cerevisiae
Journal of Biotechnology
한지숙39
2019Development of an efficient cytosolic isobutanol production pathway in Saccharomyces cerevisiae by optimizing copy numbers and expression of the pathway genes based on the toxic effect of α-acetolactate
Scientific Reports
한지숙37
2021High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate 생물화학 공정기술 › 발효공정기술
Metabolic Engineering
김준원, 한지숙35
2023Efficient production of natural sunscreens shinorine, porphyra-334, and mycosporine-2-glycine in Saccharomyces cerevisiae
Metabolic Engineering
유동원, 한지숙31
2015Improvement of Glucose Uptake Rate and Production of Target Chemicals by Overexpressing Hexose Transporters and Transcriptional Activator Gcr1 in Saccharomyces cerevisiae
Applied and Environmental Microbiology
한지숙31
2016Improvement of isobutanol production in Saccharomyces cerevisiae by increasing mitochondrial import of pyruvate through mitochondrial pyruvate carrier
Applied Microbiology and Biotechnology
한지숙30
2023Synthetic biology tools for engineering Corynebacterium glutamicum 생물화학 공정기술 › 대사공학기술
Computational and Structural Biotechnology Journal
서상우27
2015The production of ω-hydroxy palmitic acid using fatty acid metabolism and cofactor optimization in Escherichia coli 생물화학 공정기술 › 대사공학기술
Applied Microbiology and Biotechnology
김준원24
2023Engineering Yarrowia lipolytica for sustainable ricinoleic acid production: A pathway to free fatty acid synthesis
Metabolic Engineering
한지숙24
2019Production of 12-hydroxy dodecanoic acid methyl ester using a signal peptide sequence-optimized transporter AlkL and a novel monooxygenase 생물화학 공정기술 › 대사공학기술
Bioresource Technology
김준원23
2016GSF2 deletion increases lactic acid production by alleviating glucose repression in Saccharomyces cerevisiae
Scientific Reports
한지숙23
2016Systems biology for understanding and engineering of heterotrophic oleaginous microorganisms 생물화학 공정기술 › 대사공학기술
Biotechnology Journal
김준원21
2018Polymeric solvent engineering for gram/liter scale production of a water-insoluble isoflavone derivative, (S)-equol 생물화학 공정기술 › 효소생물 공정기술
Applied Microbiology and Biotechnology
김준원21
2016Redirection of pyruvate flux toward desired metabolic pathways through substrate channeling between pyruvate kinase and pyruvate-converting enzymes in Saccharomyces cerevisiae
Scientific Reports
한지숙21
2021Application of Random Mutagenesis and Synthetic FadR Promoter for de novo Production of ω-Hydroxy Fatty Acid in Yarrowia lipolytica
Frontiers in Bioengineering and Biotechnology
김준원20
2021Synthetic cellular communication-based screening for strains with improved 3-hydroxypropionic acid secretion 생물화학 공정기술 › 대사공학기술
Lab on a Chip
서상우20
2024Advancements in Biological Conversion of C1 Feedstocks: Sustainable Bioproduction and Environmental Solutions
ACS Synthetic Biology
한지숙20

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교수 6

이종민 · 서상우 · 한지숙 · 정상택 · 유동원 · 김준원

논문 71

Efficient production of natural sunscreens shinorine, porphyra-334, an · High-yield production of (R)-acetoin in Saccharomyces cerevisiae by de · Engineering Yarrowia lipolytica for sustainable ricinoleic acid produc · Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae · Improvement of Glucose Uptake Rate and Production of Target Chemicals · Synthetic biology tools for engineering Corynebacterium glutamicum · Efficient production of 2,3-butanediol in Saccharomyces cerevisiae by · Synthetic redesign of Corynebacterium glutamicum for 1,4-butanediol pr · Synthetic translational coupling system for accurate and predictable p · Polymeric solvent engineering for gram/liter scale production of a wat · Engineering Yarrowia lipolytica for the production of β-carotene by ca · Synthetic cellular communication-based screening for strains with impr · Synthetic scaffold based on a cohesin–dockerin interaction for improve · Metabolic engineering of Saccharomyces cerevisiae for the production o · Synthetic auxotrophs for stable and tunable maintenance of plasmid cop · Computationally efficient dynamic simulation of cellular kinetics via · Engineering Vibrio sp. SP1 for the production of carotenoids directly · In silico identification of metabolic engineering strategies for impro · Redirection of pyruvate flux toward desired metabolic pathways through · Synthetic biosensor accelerates evolution by rewiring carbon metabolis · Exploiting transcriptomic data for metabolic engineering: toward a sys · Efficient production of optically pure (2S,3S)-butanediol in Saccharom · Independent component analysis of E. coli's transcriptome reveals the · Efficient (S)-acetoin production in Saccharomyces cerevisiae by modula · Efficient Production of the Colorless Carotenoid Phytoene in Yarrowia · Constructing multi‐enzymatic cascade reactions for selective productio · Production of 12-hydroxy dodecanoic acid methyl ester using a signal p · High-titer retinal production in Yarrowia lipolytica via redox enginee · Efficient production of lycopene in Saccharomyces cerevisiae by enzyme · Efficient production of retinol in Yarrowia lipolytica by increasing s · A framework for building a synthetic cell from the SynCell Asia Initia · Metabolic Engineering of Saccharomyces cerevisiae for Production of Sh · Natural transformation of Vibrio natriegens with large genetic cluster · Engineering Yarrowia lipolytica for enhanced lipid productivity in nut · The production of ω-hydroxy palmitic acid using fatty acid metabolism · A Vibrio-based microbial platform for accelerated lignocellulosic suga · Improvement of d ‐Lactic Acid Production in Saccharomyces cerevisiae U · Systems biology for understanding and engineering of heterotrophic ole · Synthetic biology for evolutionary engineering: from perturbation of g · Improvement of isobutanol production in Saccharomyces cerevisiae by in · Pathway optimization by re-design of untranslated regions for L-tyrosi · Dynamic control of the plasmid copy number maintained without antibiot · Systems assessment of transcriptional regulation on central carbon met · Generation of a Vibrio-based platform for efficient conversion of raff · Design and optimization of genetically encoded biosensors for high-thr · Precise flux redistribution to glyoxylate cycle for 5-aminolevulinic a · Efficient production of d-lactate from methane in a lactate-tolerant s · Engineering of Yarrowia lipolytica as a platform strain for producing · Development of an efficient cytosolic isobutanol production pathway in · GSF2 deletion increases lactic acid production by alleviating glucose · Predictive combinatorial design of mRNA translation initiation regions · Promoters inducible by aromatic amino acids and γ-aminobutyrate (GABA) · Synthetic redesign of Escherichia coli for cadaverine production from · Efficient production of acetoin in Saccharomyces cerevisiae by disrupt · One-Pot Biocatalytic Route from Alkanes to α,ω-Diamines by Whole-Cell · Advancements in Biological Conversion of C1 Feedstocks: Sustainable Bi · Reconstruction of a high‐quality metabolic model enables the identific · Metabolic engineering and adaptive evolution for efficient production · Application of Random Mutagenesis and Synthetic FadR Promoter for de n · Metabolic Engineering of Yarrowia lipolytica for Enhanced Production o 외 11개

학문분야 1

Molecular Biology