SNU CBE

출아효모(Saccharomyces cerevisiae) saccharomyces cerevisiae

키워드 · 생명공학·합성생물학

26학부 논문
3교수
73억 국가 R&D(2015–24)
소규모증가율
27.46%서울대 비중

대표적 산업용 효모로, 대사공학을 통해 라이코펜·젖산 등 고부가 화합물을 생산하는 미생물 숙주로 쓰인다.

연도별 학부 논문

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국가 R&D 과제 동향 (NTIS, 억 원)

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2015–2024 과제 레코드 70건 · 10년 73억 · 2015–19 대비 2020–24 소규모 · 대학 수행 75.5% · 서울대(본교) 27.46%. 매칭: 영문 키워드 'saccharomyces cerevisiae', 국문 '출아효모', '사카로마이세스', '효모대사공학'. 기관운영비·인력양성·출연연 주요사업비 등 과제 아닌 레코드는 뺐다.

매칭 과제의 NTIS 표준분류(1순위, 연구비 비중): 생명과학 > 생물공학 27% · 생명과학 > 분자세포생물학 21% · 농림수산식품 > 식품과학 21% · 생명과학 > 산업바이오 13%

최근 주요 과제 (2022–2024, 연차 정부연구비 순)

연도과제수행기관부처억
2023비사보롤 생산용 재조합 Saccharomyces cerevisae 기반 LMO 고도화 및 안전성 평가 연구서울과학기술대학과학기술정보통신부3.1
2023제주 자생 프로바이오틱 효모 발굴 및 제품화를 위한 대량생산공정 개발(주)바이오크래프트산업통상자원부3.0
2024생물공정 기반 MAA 대량생산 및 화장품 소재 가치화(주)아모레퍼시픽보건복지부2.2
2023효모 대사공학을 이용한 천연 자외선 차단 소재 생산서울대학과학기술정보통신부2.0
2023수입 의존 소재 자립화를 위한 제주 자생 발효 효모 개발 및 지역 특화 식음료의 개발(주)바이오크래프트중소벤처기업부1.9
2023효모에서 단백질 인산화에 의한 자가포식 조절 기전 연구서울대학과학기술정보통신부1.5
2023과일 가공 공정 연계 국내형 그린 바이오리파이너리를 위한 효모 대사공학 원천기술 개발 및 고부가 식품 및 바이오화학 소재의 생산경북대학과학기술정보통신부1.5
2023해조류 유래 기능성 아미노산의 생물공학적 생산 플랫폼 고도화 및 식품 소재화전남대학과학기술정보통신부1.5

교수

교수연구분야논문2022년 이후
한지숙생물 및 환경264
김준원생물 및 환경10
유동원고분자 및 유기 소재 · 생물 및 환경11

함께 나오는 키워드

아세토인 생산 카제인 키나아제 2(CK2) 마이코스포린 유사 아미노산(MAA) 천연 자외선 차단제 시노린 아이소부탄올 생산 2,3-부탄디올 생산 D-젖산 생산 젖산 내성 대사공학

연결되는 NTIS 분류

생물화학 공정기술 1

논문 (최신순)

연도논문학부 저자피인용
2026Efficient production of optically pure (2S,3S)-butanediol in Saccharomyces cerevisiae
Biotechnology and Bioprocess Engineering
한지숙0
2025Efficient (S)-acetoin production in Saccharomyces cerevisiae by modulating α-acetolactate decarboxylase stereospecificity
Bioresource Technology
한지숙7
2024Efficient production of (S)-limonene and geraniol in Saccharomyces cerevisiae through the utilization of an Erg20 mutant with enhanced GPP accumulation capability
Metabolic Engineering
한지숙25
2023Efficient production of natural sunscreens shinorine, porphyra-334, and mycosporine-2-glycine in Saccharomyces cerevisiae
Metabolic Engineering
유동원, 한지숙31
2021High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate 생물화학 공정기술 › 발효공정기술
Metabolic Engineering
김준원, 한지숙35
2021Efficient production of shinorine, a natural sunscreen material, from glucose and xylose by deleting HXK2 encoding hexokinase in Saccharomyces cerevisiae
FEMS Yeast Research
한지숙20
2020Differential activation mechanisms of two isoforms of Gcr1 transcription factor generated from spliced and un-spliced transcripts inSaccharomyces cerevisiae
Nucleic Acids Research
한지숙17
2019Development of an efficient cytosolic isobutanol production pathway in Saccharomyces cerevisiae by optimizing copy numbers and expression of the pathway genes based on the toxic effect of α-acetolactate
Scientific Reports
한지숙37
2018Efficient production of lycopene in Saccharomyces cerevisiae by enzyme engineering and increasing membrane flexibility and NAPDH production
Applied Microbiology and Biotechnology
한지숙131
2018Activation of Haa1 and War1 transcription factors by differential binding of weak acid anions inSaccharomyces cerevisiae
Nucleic Acids Research
한지숙62
2018Metabolic Engineering of Saccharomyces cerevisiae for Production of Shinorine, a Sunscreen Material, from Xylose
ACS Synthetic Biology
한지숙47
2017Improvement of d ‐Lactic Acid Production in Saccharomyces cerevisiae Under Acidic Conditions by Evolutionary and Rational Metabolic Engineering
Biotechnology Journal
한지숙97
2017CK2-dependent phosphorylation positively regulates stress-induced activation of Msn2 in Saccharomyces cerevisiae
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
한지숙6
2016Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase
Scientific Reports
한지숙88
2016Improvement of isobutanol production in Saccharomyces cerevisiae by increasing mitochondrial import of pyruvate through mitochondrial pyruvate carrier
Applied Microbiology and Biotechnology
한지숙30
2016GSF2 deletion increases lactic acid production by alleviating glucose repression in Saccharomyces cerevisiae
Scientific Reports
한지숙23
2016Redirection of pyruvate flux toward desired metabolic pathways through substrate channeling between pyruvate kinase and pyruvate-converting enzymes in Saccharomyces cerevisiae
Scientific Reports
한지숙21
2016Role of CK2-dependent phosphorylation of Ifh1 and Crf1 in transcriptional regulation of ribosomal protein genes in Saccharomyces cerevisiae
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
한지숙19
2015Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyces cerevisiae
Applied Microbiology and Biotechnology
한지숙119
2015Efficient production of 2,3-butanediol in Saccharomyces cerevisiae by eliminating ethanol and glycerol production and redox rebalancing
Metabolic Engineering
한지숙113
2015Improvement of Glucose Uptake Rate and Production of Target Chemicals by Overexpressing Hexose Transporters and Transcriptional Activator Gcr1 in Saccharomyces cerevisiae
Applied and Environmental Microbiology
한지숙31
2015Promoters inducible by aromatic amino acids and γ-aminobutyrate (GABA) for metabolic engineering applications in Saccharomyces cerevisiae
Applied Microbiology and Biotechnology
한지숙20
2015CK2 Kinase-dependent Regulation of Stress-responsive Transcription Factors in Saccharomyces cerevisiae
한국미생물학회 학술대회논문집
한지숙0
2014Metabolic engineering of Saccharomyces cerevisiae for the production of isobutanol and 3-methyl-1-butanol
Applied Microbiology and Biotechnology
한지숙87
2014Synthetic scaffold based on a cohesin–dockerin interaction for improved production of 2,3-butanediol in Saccharomyces cerevisiae
Journal of Biotechnology
한지숙39
2014CK 2‐dependent inhibitory phosphorylation is relieved by Ppt 1 phosphatase for the ethanol stress‐specific activation of Hsf 1 in S accharomyces cerevisiae
Molecular Microbiology
한지숙21

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한지숙

논문 26

Efficient production of natural sunscreens shinorine, porphyra-334, an · Metabolic Engineering of Saccharomyces cerevisiae for Production of Sh · Improvement of d ‐Lactic Acid Production in Saccharomyces cerevisiae U · High-yield production of (R)-acetoin in Saccharomyces cerevisiae by de · Efficient production of shinorine, a natural sunscreen material, from · GSF2 deletion increases lactic acid production by alleviating glucose · Metabolic engineering and adaptive evolution for efficient production · Efficient production of lycopene in Saccharomyces cerevisiae by enzyme · Metabolic engineering of Saccharomyces cerevisiae for the production o · Efficient production of optically pure (2S,3S)-butanediol in Saccharom · Improvement of isobutanol production in Saccharomyces cerevisiae by in · Improvement of Glucose Uptake Rate and Production of Target Chemicals · Efficient (S)-acetoin production in Saccharomyces cerevisiae by modula · Role of CK2-dependent phosphorylation of Ifh1 and Crf1 in transcriptio · CK2 Kinase-dependent Regulation of Stress-responsive Transcription Fac · Efficient production of 2,3-butanediol in Saccharomyces cerevisiae by · Synthetic scaffold based on a cohesin–dockerin interaction for improve · CK2-dependent phosphorylation positively regulates stress-induced acti · Development of an efficient cytosolic isobutanol production pathway in · Differential activation mechanisms of two isoforms of Gcr1 transcripti · Efficient production of acetoin in Saccharomyces cerevisiae by disrupt · Activation of Haa1 and War1 transcription factors by differential bind · Promoters inducible by aromatic amino acids and γ-aminobutyrate (GABA) · Redirection of pyruvate flux toward desired metabolic pathways through · CK 2‐dependent inhibitory phosphorylation is relieved by Ppt 1 phospha · Efficient production of (S)-limonene and geraniol in Saccharomyces cer