SNU CBE

Radiology, Nuclear Medicine and Imaging

학문분야 · Medicine

교수

교수연구분야논문
정상택생물 및 환경33
현택환무기 및 전기전자 소재2
성영은무기 및 전기전자 소재1
황석연생물 및 환경1

연구주제

Monoclonal and Polyclonal Antibodies Research (32) · Radiopharmaceutical Chemistry and Applications (2) · Effects of Radiation Exposure (1)

논문 (피인용 상위 30)

연도논문학부 저자피인용
2014High-resolution antibody dynamics of vaccine-induced immune responses
Proceedings of the National Academy of Sciences
정상택171
2019Boosting therapeutic potency of antibodies by taming Fc domain functions
Experimental & Molecular Medicine
정상택139
2020Epitaxially Strained CeO2/Mn3O4 Nanocrystals as an Enhanced Antioxidant for Radioprotection
Advanced Materials
성영은, 현택환129
2021Recent Achievements and Challenges in Prolonging the Serum Half-Lives of Therapeutic IgG Antibodies Through Fc Engineering
BioDrugs
정상택68
2022An Fc variant with two mutations confers prolonged serum half-life and enhanced effector functions on IgG antibodies
Experimental & Molecular Medicine
정상택68
2014Aglycosylated full-length IgG antibodies: steps toward next-generation immunotherapeutics
Current Opinion in Biotechnology
정상택66
2016The Highly Evolvable Antibody Fc Domain
Trends in biotechnology
정상택53
2015Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form 나노 화학공정기술 › 나노복합재 제조기술
Scientific Reports
현택환48
2017Engineered aglycosylated full-length IgG Fc variants exhibiting improved FcγRIIIa binding and tumor cell clearance
mAbs
정상택33
2021A short PEG linker alters the in vivo pharmacokinetics of trastuzumab to yield high-contrast immuno-PET images
Journal of Materials Chemistry B
정상택25
2021A human antibody against human endothelin receptor type A that exhibits antitumor potency
Experimental & Molecular Medicine
정상택22
2017A synthetic library for rapid isolation of humanized single-domain antibodies
Biotechnology and Bioprocess Engineering
정상택22
2017Optical spectroscopic imaging for cell therapy and tissue engineering
Applied Spectroscopy Reviews
황석연22
2025Engineering FcRn binding kinetics dramatically extends antibody serum half-life and enhances therapeutic potential
Journal of Biological Engineering
정상택18
2020Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies
International Journal of Molecular Sciences
정상택18
2015Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding
Molecular Immunology
정상택16
2024Escherichia coli and Pichia pastoris : microbial cell-factory platform for full-length IgG production
Critical Reviews in Biotechnology
정상택14
2014Engineering an aglycosylated Fc variant for enhanced FcγRI engagement and pH-dependent human FcRn binding
Biotechnology and Bioprocess Engineering
정상택14
2020Reprogramming the Constant Region of Immunoglobulin G Subclasses for Enhanced Therapeutic Potency against Cancer
Biomolecules
정상택13
2019Computer‐based engineering of thermostabilized antibody fragments
AIChE Journal
정상택12
2023Unlocking the Power of Complement-Dependent Cytotoxicity: Engineering Strategies for the Development of Potent Therapeutic Antibodies for Cancer Treatments
BioDrugs
정상택10
2023Effective clearance of rituximab-resistant tumor cells by breaking the mirror-symmetry of immunoglobulin G and simultaneous binding to CD55 and CD20
Scientific Reports
정상택10
2023Isolation and characterization of single domain antibodies from banded houndshark (Triakis scyllium) targeting SARS-CoV-2 spike RBD protein
Fish & Shellfish Immunology
정상택7
2019Optimal combination of beneficial mutations for improved ADCC effector function of aglycosylated antibodies
Molecular Immunology
정상택6
2021Structural Study on the Impact of S239D/I332E Mutations in the Binding of Fc and FcγRIIIa
Biotechnology and Bioprocess Engineering
정상택6
2025Advanced human FcRn knock-in mice for pharmacokinetic profiling of therapeutic antibodies
Scientific Reports
정상택4
2015Engineering antibodies for dual specificity and enhanced potency
Biotechnology and Bioprocess Engineering
정상택4
2025Engineered neutrophil engagers overcome IgA limitations and reprogram resting neutrophils for cancer immunotherapy
Journal of Biological Engineering
정상택3
2020Engineered human FcγRIIa fusion: A novel strategy to extend serum half‐life of therapeutic proteins
Biotechnology and Bioengineering
정상택3
2018Escherichia coli inner membrane display system for high‐throughput screening of dimeric proteins
Biotechnology and Bioengineering
정상택3

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교수 1

정상택

연구주제 3

Monoclonal and Polyclonal Antibodies Research · Radiopharmaceutical Chemistry and Applications · Effects of Radiation Exposure