Rod and Vesicular Structures of Cyclosophoraose-Based Ionic Self-assembly

In the present study, we introduce a building block based onmicrobial carbohydrate. Cys were isolated and purified from Rhizobium trifolii TA-1as described in the Experimental section. The native Cyswas modified with quaternary ammonium (QA), and thesynthesized QA–Cys was used as a cationic participant inionic self-assembly. The modified structures were investi-gated using elemental analysis (EA) and nuclear magneticresonance (NMR) spectroscopy (Figure 1). Nitrogen con-tents (N%) of QA–Cys were measured to be 4.28 using anelemental analyzer. The degree of substitution (DS) valuewas determined to be 0.92 by measurement of nitrogen con-tents and calculated according to the following equation: